Symbol
Name
ID

Ifnar1
interferon (alpha and beta) receptor 1
MGI:107658

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased T cell apoptosis

decreased NK cell number

increased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased Ly6C high monocyte number

increased leukocyte cell number

abnormal mononuclear phagocyte morphology

abnormal osteoclast morphology

abnormal immunoglobulin level

decreased IgG1 level

decreased IgG2a level

decreased IgG3 level

decreased IgM level

abnormal NK cell physiology

impaired natural killer cell mediated cytotoxicity

abnormal CD8-positive, alpha-beta T cell physiology

abnormal macrophage physiology

Availability

Mouse Genotype

Ifnar1^m1Btlr/Ifnar1^m1Btlr

Ifnar1^tm1Agt/Ifnar1^tm1Agt

Ifnar1^tm1Pjh/Ifnar1^tm1Pjh

Cd19^tm1(cre)Cgn/Cd19⁺
Ifnar1^tm1Uka/Ifnar1^tm1Uka (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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